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Possible natural gas leak causes explosion at Liberty Dialysis - Waxahachie ... - Waxahachie Daily Light |
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By Scott Dorsett/ Daily Light
Liberty Dialysis natural gas explosion destroys 'heart of clinic'
The back of Liberty Dialysis on U.S. Highway 77 was rocked by an explosion early Tuesday morning. The cause was a natural gas leak, said Waxahachie Fire Chief Ricky Boyd.
Location
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Posted: Tuesday, July 21, 2015 8:41 am | Updated: 7:28 pm, Tue Jul 21, 2015.
Liberty Dialysis natural gas explosion destroys 'heart of clinic' By Shelly Conlon and Andrew Branca The Daily Light managing editor and staff writer Waxahachie Newspapers Inc.
A natural gas leak caused an early morning explosion at Liberty Dialysis in Waxahachie off U.S. Highway 77 behind Dickey's Barbecue Pit, said Waxahachie Fire Chief Ricky Boyd at the scene.
“You can see the back wall is basically all blown off, so it was quite an explosion,” Boyd said. “We're very fortunate that nobody was in the back of the building when it happened. I've seen explosions before, and this is pretty big.”
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Posted in Ellis county, Waxahachie, Police on Tuesday, July 21, 2015 8:41 am. Updated: 7:28 pm. | Tags: Gas Leak, Area, Canada, Fire, Fire Chief, Republic Bank Trust Company, Ac Power Plugs And Sockets, Ad Hominem, Allen Street, Canada Day, Health_medical_pharma, Ricky Boyd, Cindy Roberts, Business_finance, Dialysis, Possible Natural Gas Leak, U.s. Highway, Waxahachie Fire Chief, United States, Waxahachie Fire Department, Nurse Manager, Mapable
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Medications Contribute to Phosphate Intake - Renal and Urology News - Renal and Urology News |
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July 21, 2015
Among the phosphate-containing medicinal products prescribed to chronic kidney disease patients, 76% may contain absorbable phosphate.
Beyond foods and drinks, medications may be a significant source of phosphate that adds to patients' daily load. A new study finds several medications prescribed to chronic kidney disease (CKD)patients, particularly long-term ones, contain absorbable phosphate.
Investigators led by Gianluca Trifiro, MD, Assistant Professor of Pharmacology at the University of Messina in Milan, Italy, identified 1,989 CKD patients from the Arianna database, a local health database of almost 400,000 people living in Southern Italy. All drug prescriptions provided to these patients were evaluated and classified as to whether they contained absorbable phosphate, their dosage, and route of administration. The researchers also determined where the absorbable phosphate resided in the drug: in the active ingredients, in the counter-ion, or in the excipient (typically, a pharmacologically inert binder).
Of all medicinal products prescribed to CKD patients, only 9% contained phosphate, according to findings published in Nutrition, Metabolism & Cardiovascular Diseases. Yet 70% of CKD patients were prescribed at least 1 medication containing absorbable phosphate during the 6 years of follow up. Their usage was higher than that of non-CKD patients.
Additional findings highlight a concerning degree of exposure. Most CKD patients were prescribed phosphate-containing drugs targeting the gastrointestinal or cardiovascular system. Duration of use was typically long-term: a median 232 and 224 days, respectively. Additionally, many medications were taken orally, the most common route of the drugs with absorbable phosphate.
Results also suggested that patients with advanced CKD may have a higher phosphate burden than those with early stage CKD. About 10% of patients with CKD stages 4–5 had an estimated intake of 80 mg or more phosphate a day from medication, which is considered high, and 2% had an estimated intake of 150 mg or more. The investigators estimated that these amounts represent 13% and 25% excess phosphate intake per day, respectively.
“In patients with renal disease it is essential to reduce blood phosphate levels as hyperphosphatemia has been shown to increase the risk of cardiovascular-related morbidity,” the researchers stated. “The biochemical mechanism for this is likely to be triggered in early CKD stages as the reduced capacity of the kidney to excrete phosphate stimulates the release of fibroblast growth factor 23 (FGF-23) which in turn promotes renal phosphate excretion in order to maintain homeostasis.”
In 94% of the medications examined, the source of absorbable phosphate was the excipient of the drug, not the active components. This fact has several important implications. For example, exact amounts of phosphate may not be listed in products. Given this lack of detail, clinicians have no way of making informed medication choices for their patients. Substituting phosphate-free excipients is a potential solution that should be explored, according to the investigators
Source
- Sultana, J; Musazzi, UM; Ingrasciotta, Y; et al. Nutrition, Metabolism & Cardiovascular Diseases, June 2015; doi: 10.1016/j.numecd.2015.06.001.
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Medications Contribute to Phosphate Intake - Renal and Urology News |
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July 21, 2015
Among the phosphate-containing medicinal products prescribed to chronic kidney disease patients, 76% may contain absorbable phosphate.
Beyond foods and drinks, medications may be a significant source of phosphate that adds to patients' daily load. A new study finds several medications prescribed to chronic kidney disease (CKD)patients, particularly long-term ones, contain absorbable phosphate.
Investigators led by Gianluca Trifiro, MD, Assistant Professor of Pharmacology at the University of Messina in Milan, Italy, identified 1,989 CKD patients from the Arianna database, a local health database of almost 400,000 people living in Southern Italy. All drug prescriptions provided to these patients were evaluated and classified as to whether they contained absorbable phosphate, their dosage, and route of administration. The researchers also determined where the absorbable phosphate resided in the drug: in the active ingredients, in the counter-ion, or in the excipient (typically, a pharmacologically inert binder).
Of all medicinal products prescribed to CKD patients, only 9% contained phosphate, according to findings published in Nutrition, Metabolism & Cardiovascular Diseases. Yet 70% of CKD patients were prescribed at least 1 medication containing absorbable phosphate during the 6 years of follow up. Their usage was higher than that of non-CKD patients.
Additional findings highlight a concerning degree of exposure. Most CKD patients were prescribed phosphate-containing drugs targeting the gastrointestinal or cardiovascular system. Duration of use was typically long-term: a median 232 and 224 days, respectively. Additionally, many medications were taken orally, the most common route of the drugs with absorbable phosphate.
Results also suggested that patients with advanced CKD may have a higher phosphate burden than those with early stage CKD. About 10% of patients with CKD stages 4–5 had an estimated intake of 80 mg or more phosphate a day from medication, which is considered high, and 2% had an estimated intake of 150 mg or more. The investigators estimated that these amounts represent 13% and 25% excess phosphate intake per day, respectively.
“In patients with renal disease it is essential to reduce blood phosphate levels as hyperphosphatemia has been shown to increase the risk of cardiovascular-related morbidity,” the researchers stated. “The biochemical mechanism for this is likely to be triggered in early CKD stages as the reduced capacity of the kidney to excrete phosphate stimulates the release of fibroblast growth factor 23 (FGF-23) which in turn promotes renal phosphate excretion in order to maintain homeostasis.”
In 94% of the medications examined, the source of absorbable phosphate was the excipient of the drug, not the active components. This fact has several important implications. For example, exact amounts of phosphate may not be listed in products. Given this lack of detail, clinicians have no way of making informed medication choices for their patients. Substituting phosphate-free excipients is a potential solution that should be explored, according to the investigators
Source
- Sultana, J; Musazzi, UM; Ingrasciotta, Y; et al. Nutrition, Metabolism & Cardiovascular Diseases, June 2015; doi: 10.1016/j.numecd.2015.06.001.
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Research delivers insight into the dialysis catheters market in the US that is ... - WhaTech |
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- Details
- WhaTech Channel: Medical Market Research Reports
- Published on Tuesday, 21 July 2015 20:57
- Submitted by Pawan Kumar WhaTech Agency
- News from: Big Market Research - Market Research Reports
- Page views: Not Yet Available
Dialysis catheter is a device required to provide vascular access to dialysis equipment for carrying out dialysis. It is inserted into a vein in the groin (under the collarbone, or in the neck).
This catheter has two separate tubes, one of which carries blood from a patient to the dialysis machine, and the other helps return blood to the body. This device can be used for both long-term and short-term access; however, it is not recommended for long-term access.
The dialysis catheters market in the US to grow at a CAGR of 2.11% over the period 2015-2019.
Read more details at:http://www.bigmarketresearch.com/dialysis-catheters-in-the-us-2015-2019-market
Covered in this report
The Dialysis catheters market in the US is segmented into two based on product type: acute dialysis catheters and chronic dialysis catheters.
The Dialysis Catheters Market in the US 2015-2019, has been prepared based on an in-depth market analysis with inputs from industry experts. It covers the landscape of the dialysis catheters market in the US and its growth prospects in the coming years.
The report includes a discussion of the key vendors operating in this market.
Table of Contents:
1 Executive Summary
2 List of Abbreviations
3 Scope of the Report
4 Market Research Methodology
5 Introduction
6 Market Landscape
7 Vascular Access for Dialysis
8 Market Segmentation by Product
Key vendors
• AngioDynamics
• C.R. Bard
• Covidien
• Medical Components
Other prominent vendors
• Argon Medical Devices
• Baxter International
• Merit Medical Systems
• Teleflex
Market driver
• Growing ESRD and CKD patient population
• For a full, detailed list, view our report
Market challenge
• Presence of alternative devices
• For a full, detailed list, view our report
Market trend
• Increase in use of minimally invasive techniques
• For a full, detailed list, view our report
Key questions answered in this report
• What will the market size be in 2019 and what will the growth rate be?
• What are the Key market trends?
• What is driving this market?
• What are the challenges to market growth?
• Who are the key vendors in this market space?
• What are the market opportunities and threats faced by the key vendors?
• What are the strengths and weaknesses of the key vendors?
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